#32026R0353Commission Implementing Regulation (EU) 2026/353 of 18 February 2026 concerning the authorisation of L-histidine and L-histidine monohydrochloride monohydrate produced with Corynebacterium glutamicum KCCM 80389 as feed additives for all animal species
AI-generated summary for informational purposes only. Not legal advice. See the original source for the authoritative text.
This regulation authorises two forms of L-histidine (free base and monohydrochloride monohydrate) produced via fermentation with Corynebacterium glutamicum KCCM 80389 as nutritional additives (amino acids) and as sensory additives (flavouring compounds) for all animal species. The additives are considered safe for target animals when used according to nutritional needs, for consumers, and for the environment. They are not skin irritants or sensitisers. For ruminants, the substances must be rumen-protected to be effective. Use in drinking water is permitted for nutritional purposes but carries hygiene concerns that fall under separate feed hygiene rules. Maximum recommended content for flavouring use is 25 mg/kg in complete feed with 12% moisture.
AI-generated summary. May contain errors. Refer to official sources for legal decisions.
Key Changes
- Authorises 3c353 (L-histidine ≥90%) and 3c354 (L-histidine monohydrochloride monohydrate ≥98% with ≥72% histidine) produced with strain KCCM 80389
- Histamine limit set at ≤100 ppm in both additives
- Requires rumen protection for both substances when fed to ruminants
+ 3 more changes with Pro
Obligations
What this law requires
Feed additive manufacturers must ensure L-histidine and L-histidine monohydrochloride monohydrate are produced with Corynebacterium glutamicum KCCM 80389 strain as specified
When using L-histidine or L-histidine monohydrochloride monohydrate as nutritional additives in ruminant feed, the substances must be protected against degradation in the rumen
Label of feed additives must indicate the recommended maximum content of L-histidine and L-histidine monohydrochloride monohydrate when used as flavouring compounds
When recommended maximum contents are exceeded in premixtures, certain information must be indicated on the label of the premixtures concerned
Maximum recommended content for flavouring use is 25 mg/kg in complete feed with 12% moisture content